Accumbal GABA<sub>A</sub> and GABA<sub>B</sub> receptors each inhibit acetylcholine efflux without affecting dopamine efflux in the nucleus accumbens of freely moving rats
نویسندگان
چکیده
منابع مشابه
PM319. δ1, δ2 and μ2, but not μ1 receptors, exert an inhibitory role in regulation of acetylcholine efflux in the nucleus accumbens of freely moving rats
Objective: Cholinergic neurons in the nucleus accumbens (NAc) express δ and μ receptors that are thought to inhibit neural activity (Britt & McGehee, 2008). δ and μ receptors are divided into δ1 and δ2 receptors and μ1 and μ2 receptors, respectively. Therefore, we analysed the roles of δ and μ receptor subtypes in regulating accumbal acetylcholine (ACh) efflux using in vivo microdialysis. Metho...
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Accumbal dopamine plays an important role in physiological responses and diseases such as schizophrenia, Parkinson's disease, and depression. Since the nucleus accumbens contains different neurotransmitters, it is important to know how they interact with dopaminergic function: this is because modifying accumbal dopamine has far-reaching consequences for the treatment of diseases in which accumb...
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ژورنال
عنوان ژورنال: Proceedings for Annual Meeting of The Japanese Pharmacological Society
سال: 2019
ISSN: 2435-4953
DOI: 10.1254/jpssuppl.92.0_1-p-002